MDMA (ecstasy)

MDMA (ecstasy)

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Overview

3,4-Methylenedioxymethamphetamine (MDMA) is a common recreational drug. It is also known as Molly or Ecstasy, and to a lesser extent, Mandy or Adam. MDMA is also beginning Phase 3 trials with the US FDA for the treatment of PTSD.

“MDMA’s risk profile is low enough to justify further explorations in clinical trial settings. However, this only applies to carefully designed research contexts with screened adult subjects, and does not apply to any other use of MDMA.

What is MDMA?

MDMA is a drug that can make people feel euphoric and empathetic. Molly is the street name for powder or crystal MDMA, often sold in capsules. Ecstasy is the street name for pill form of MDMA.

Rabbi Zalman Schachter-Shalomi publicly compared psychedelics to a sacrament. Of MDMA he would later say for publication, “I felt the great delight of loving the universe and being loved by the universe.

Brother David Steindl-Rast told the Los Angeles Times the MDMA experience was “like climbing all day in the fog and then suddenly, briefly seeing the mountain peak for the first time. There are no shortcuts to the awakened attitude, and it takes daily work and effort. But the drug gives you a vision, a glimpse of what you are seeking.

Molly vs Ecstasy vs MDMA

MDMA is the official chemical name for the pure chemical compound – in an ideal world, Molly would be 100% pure MDMA. Molly is a street name for MDMA in powder form, often contained in clear capsules. “Molly” doesn’t mean pure. Ecstasy is a street name for MDMA in pill/tablet form.

Caution: Drugs sold as MDMA, Molly or Ecstasy are often impure. 87% of “Molly” analyzed by the DEA between 2009 and 2013 contained 0% MDMA, instead mostly containing “bath salts.”

Quick MDMA Info

Topic Info
Safety in research Yes, safe in research
Chemical name 3,4-Methylenedioxymethamphetamine
Street names Molly, Ecstasy, X, Mandy
Risks 1. Fake MDMA 2. Overheating 3. Drinking too much water
Desirable effects (~3-7 hours) Eurphoria, feelings of authenticity, empathy for others
Side effects (~3-7 hours) Dry mouth, anxiety, thirst
Medical use PTSD treatment combined with therapy

Is MDMA safe?

MAPS states “in laboratory studies, pure MDMA has been proven sufficiently safe for human consumption when taken a limited number of times in moderate doses.” MDMA seems to be about as safe as skydiving, and a regulated environment would likely make MDMA safer. Regulation could reduce the risk of fake MDMA. MDMA appears to be safer than most other illegal drugs, though all drugs can be harmful under specific circumstances. MDMA is safer if you follow harm reduction guidelines.

“Nonhuman animal studies have shown MDMA (structurally similar to some classical hallucinogens, but with a substantially different pharmacological mechanism of action) to have neurotoxic effects at high doses, although MDMA has been judged to be safe for human administration in the context of several therapeutic and basic human research studies.

Advocates of MDMA-assisted psychotherapy stress the differences between heavy recreational drug users and patients who are carefully screened and take the medication two or three times in a supervised setting. Statistics from emergency room visits or reports of deaths attributed to Ecstasy are troubling, but they often involve users who may be simultaneously drinking alcohol and ingesting other illicit drugs. Those behind the new wave of studies point out that more than a thousand people have received MDMA in research settings without any serious problems. “There is little reason to fear,” says Rick Doblin of MAPS, the psychedelic research sponsor, “that normal therapeutic (or recreational) doses of MDMA will result in harmful functional or behavioral consequences.

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MDMA (ecstasy)

What is MDMA (Ecstasy or Molly)?

MDMA (ecstasy): MDMA, short for 3,4-methylenedioxymethamphetamine, is most commonly known as Ecstasy or Molly. It is a laboratory-made drug that produces a “high” similar to the stimulants called amphetamines. It also produces psychedelic effects, similar to the hallucinogens mescaline and LSD. MDMA first became popular in the nightclub scene, at “raves” (all-night dance parties), and music festivals or concerts. It is now used by a broader range of people. The drug’s effects generally last from 3 to 6 hours.

MDMA is a Schedule I substance, which means that the U.S. Government has determined that it has no medical benefit and a high potential for abuse. Researchers, however, continue to investigate the possible medical benefits, for example, with patients that have post-traumatic stress disorder (PTSD) and terminal cancer patients with anxiety. However, patients in those studies are under strict medical supervision.

How MDMA (Ecstasy/Molly) is Used

Most people who use MDMA take it in a pill, tablet, or capsule. The pills can be different colors and sometimes have cartoon-like images on them. Some people take more than one pill at a time, called “bumping.” The popular term “Molly” (slang for molecular) refers to the pure crystalline powder form of MDMA, usually sold in capsules. But this is mostly a marketing gimmick—testing on “Molly” seized by police shows a variety of other ingredients.

In fact, researchers and law enforcement have found that much of the Ecstasy sold today contains other harmful and possibly deadly drugs. In some recent cases, drugs sold as MDMA actually contain no MDMA at all. Frequently, MDMA is mixed with or replaced by synthetic cathinones, the chemicals in “bath salts”. Some MDMA pills, tablets, and capsules have also been found to contain caffeine, dextromethorphan (found in some cough syrups), amphetamines, PCP, or cocaine.

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